The Honest Correction

30 seconds on what peptides actually are, and what they are not.

Every claim, with its source

• Insulin is a peptide. Isolated in Toronto in 1921; first given to a patient in January 1922. Still in daily use.
• More than 80 peptide drugs are FDA-approved. Published counts range from about 80 to 130 depending on how the category is drawn. The lower bound is used here.
• Semaglutide cut major cardiac events by 20%. The SELECT trial, NEJM 2023: 17,604 people with overweight or obesity and established cardiovascular disease, without diabetes. 6.5% vs 8.0%, hazard ratio 0.80. Twenty percent is the relative reduction; the absolute reduction is 1.5 percentage points.
• BPC-157 and TB-500 are not FDA-approved. Twelve peptides were removed from the FDA's Category 2 restricted list in April 2026. Removal from that list is not approval, and does not make these drugs legal to sell for human use.

Not medical advice. Nothing here recommends taking any compound. If you are considering one, that is a conversation with your doctor.